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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
18.18
Human Site:
Y65
Identified Species:
40
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
Y65
Q
R
R
V
P
A
N
Y
A
D
G
V
Y
Q
A
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
Y65
Q
R
R
V
P
A
N
Y
A
D
G
V
Y
Q
A
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
F42
V
Q
R
Y
D
G
W
F
N
N
L
R
H
H
E
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
Y65
R
R
L
V
P
A
N
Y
A
D
G
V
Y
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
Y66
Q
R
L
V
P
A
N
Y
A
D
G
V
Y
Q
A
Chicken
Gallus gallus
XP_425053
1523
173782
Y46
L
R
L
L
P
A
N
Y
A
D
G
V
Y
Q
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
R54
A
N
R
P
S
T
R
R
L
S
R
L
F
M
R
Honey Bee
Apis mellifera
XP_624355
1492
172466
A50
L
I
R
K
M
P
A
A
Y
S
D
G
V
Y
M
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
S56
R
L
H
R
D
A
R
S
Y
Y
S
D
G
V
Y
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
S142
L
T
R
R
L
P
V
S
Y
A
D
G
V
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
100
6.6
N.A.
N.A.
N.A.
86.6
N.A.
93.3
80
N.A.
0
N.A.
6.6
6.6
6.6
13.3
P-Site Similarity:
100
100
33.3
N.A.
N.A.
N.A.
93.3
N.A.
93.3
86.6
N.A.
0
N.A.
20
6.6
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
55
10
10
46
10
0
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
19
0
0
0
0
46
19
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
46
19
10
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
28
10
28
10
10
0
0
0
10
0
10
10
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
10
0
0
0
0
46
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
46
19
0
0
0
0
0
0
0
0
0
% P
% Gln:
28
10
0
0
0
0
0
0
0
0
0
0
0
46
0
% Q
% Arg:
19
46
55
19
0
0
19
10
0
0
10
10
0
0
10
% R
% Ser:
0
0
0
0
10
0
0
19
0
19
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
37
0
0
10
0
0
0
0
46
19
10
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
46
28
10
0
0
46
19
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _